Granules
Granules typically have a size range between 0.2 to 4.0 mm depending on their subsequent use.
Synonym "Agglomeration": Agglomeration processes or in a more general term particle size enlargement
technologies are great tools to modify product properties. Agglomeration of powders is widely used to
improve physical properties like: wettability, flowability, bulk density and product appearance.
In the pharmaceutical industry, granulation refers to the act or process in which
primary powder particles are made to adhere to form larger, multiparticle entities called granules. It is the process of
collecting particles together by creating bonds between them. Bonds are formed by compression or by using a binding agent.
Granulation is extensively used in the manufacturing of tablets and pellets (or spheroids).
The granulation process combines one or more powder particles and forms a granule that will allow tableting or spheronization
process to be within required limits. This way predictable and repeatable process is possible and quality tablets or pellets can
be produced using tabletting or spheronization equipment.